This is an authoritative, comprehensive book on the fate of drug
molecules in the body, including implications for pharmacological
and clinical effects. The text provides a unique, balanced
approach, examining the specific physical and biological factors
affecting the absorption, distribution, metabolism and excretion of
drugs, together with mathematical assessment of the concentrations
in plasma and body fluids. Understanding the equations requires
little more than a basic knowledge of algebra, laws of indices and
logarithms, and very simple calculus. A companion web site contains
additional illustrations, further equations and numerous worked
examples.
Whilst this book has its roots in the highly acclaimed book of
the same name, written by Stephen Curry nearly thirty years ago, it
is essentially a new book having been restructured and largely
rewritten. This readable and informative book is an invaluable
resource for professionals and students needing to develop a
rational approach to the investigation and application of
drugs.
About the author
Stephen H. Curry is an independent consultant, teacher and writer. With extensive experience of academia and the pharmaceutical industry, he is Professor of Pharmacology and Physiology at the University of Rochester, having held appointments at the University of London, the University of Florida, and with Fisons and Astra Zeneca. He has written 4 books and over 150 publications in scientific journals, including prize-winning papers and essays. He was the founding co-editor of the Wiley-Blackwell Journal Biopharmaceutics and Drug Disposition.
Robin Whelpton is a senior lecturer at Queen Mary University of London with over thirty years teaching experience. He has written and contributed to a number of books, including co-authoring the successful Fundamentals of Analytical Toxicology published by Wiley-Blackwell in 2008, and published extensively in scientific and technical journals.
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