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Science of Synthesis: Houben-Weyl Methods of Molecular Transformations is the entirely new edition of the acclaimed reference series Houben-Weyl, the standard synthetic chemistry resource since 1909. This new edition is published in English and will comprise 48 volumes published between the years 2000 and 2008.
Science of Synthesis is a quality reference work developed by a highly esteemed editorial board to provide a comprehensive and critical selection of reliable organic and organometallic synthetic methods. This unique resource is designed to be the first point of reference when searching for a synthesis strategy.
- Contains the expertise of presently 400 leading chemists worldwide
- Critically evaluates the preparative applicability and significance of the synthetic methods
- Discusses relevant background information and provides detailed experimental procedures
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Innehållsförteckning
<p>40.1 Product Class 1: Amino Compounds<br>40.1.1 Product Subclass 1: Alkyl- and Cycloalkylamines<br>40.1.1.1 Synthesis by Reduction<br>40.1.1.1.1 Reduction of Carbonic and Carboxylic Acid Derivatives<br>40.1.1.1.2 Reductive Amination of Carbonyl Compounds<br>40.1.1.1.3 Reaction of Acetals with Organometallic Reagents<br>40.1.1.1.4 Hydroaminomethylation of Alkenes<br>40.1.1.1.5 Reduction of Nitrogen-Based Functional Groups<br>40.1.1.2 Synthesis by Substitution<br>40.1.1.2.1 Synthesis by Substitution of Hydrogen or Metals<br>40.1.1.2.2 Substitution of Carbon Functionalities via Solvolysis<br>40.1.1.2.3 Substitution of Sulfur or Phosphorus Functionalities<br>40.1.1.3 Synthesis by Addition Reactions<br>40.1.1.3.1 Hydroamination<br>40.1.1.3.2 Addition of Carbanions to Azomethines<br>40.1.1.3.3 Pericyclic Reactions Involving C=N Units<br>40.1.1.4 Synthesis by Rearrangement<br>40.1.1.5 Synthesis from Other Amino Compounds<br>40.1.1.5.1 Resolution of Chiral Amines<br>40.1.1.5.2 The Mannich Reaction<br>40.1.1.5.3 Modification of Mannich Adducts<br>40.1.1.5.4 Substitution on the Amine Nitrogen<br>40.1.2 Product Subclass 2: Propargylic Amines<br>40.1.3 Product Subclass 3: Allylic Amines<br>40.1.4 Product Subclass 4: n-Nitroge-n or n-Phosphorus-Functionalized Alkylamines (n ≥2)<br>40.1.5 Product Subclass 5: Aziridines<br>40.1.6 Product Subclass 6: Azetidines<br>40.1.7 Product Subclass 7: Ammonium Compounds and Nitrogen Ylides</p>