Giuseppe Buonocore & Carlo Valerio Bellieni 
Neonatal Pain [PDF ebook] 
Suffering, Pain, and Risk of Brain Damage in the Fetus and Newborn

PART I  Delivery and Pain.-  Gonadal Hormones and Pain Modulation.- Stress and Pregnancy: CRF as Biochemical Marker.-  Pain Control During Labour.-  PART II Fetal Pain.-  Ultrasound and Fetal Stress: Study of the Fetal Blink-Startle Reflex Evoked by Acoustic Stimuli.- Prenatal Affective Exchanges and Their Subsequent Effects in Postnatal Life.- Pain in the Fetus.- New Insights into Prenatal Stress: Immediate and Long-Term Effects on the Fetus and Their Timing.-  PART III Neonatal Pain.-  Pain Assessment and Spectral Analysis of Neonatal Crying.- Analgesic Procedures in Newborns.- Nonpharmacological Treatment of Neonatal Pain.- Sensory Saturation: An Analgesic Method.- Pharmacologic Analgesia in the Newborn.- Physical Stress Risk Agents in Incubators.- Fetal surgery analgesia.-  PART IV Pain: a Risk Factor for Brain Damage.-  Neonatal Stressors.- New Insights into Neonatal Hypersensitivity.- From the Gate-Control Theory to Brain Programs for Neonatal Pain.- PARTV Pain and Communication.- Disclosure of Pathology to the Newborn’s Family.- Communication of Diagnosis: Pain and Grief in the Experience of  Parents of Children with a Congenital Malformation.- Invest in Prenatal Life: A High-Yield Stock.

Giuseppe Buonocore is full professor of Pediatrics and Director of the Unit of Neonatology of the University Hospital of Siena. He is involved in the coordination of numerous pan-European clinical trials, as for example of the European scientific network EURAIBI (acronym for EURope Against Infant Brain Injury). His research interests are in the mechanisms of cell damage in the neonatal brain, with special reference to hypoxia, the role of oxidant radicals in neonatal diseases and in babies with birth asphyxia. Additional research interest fields are ethics in perinatology and fetal and neonatal pain prevention. His research team is funded by several agencies including the Italian Ministry of University and Scientific Research -cofinance scheme for research projects of high national interest as well as European Community : NEOBRAIN project. Author of more than 100 scientific publications in international journals with IF (’Pediatric Research’, ’Biology of Neonate’, ’Free Radical Biology and Medicine’, ’Acta Paediatrica’, ’Archives Diseases in Children’, ’ Journal of Pediatrics’ and others). He is Past-President of the European Society for Pediatric Research, and currently a member of the Editorial Board of ’Biology of Neonate’.

Dr. Bellieni, author of two chapters in the Encyclopedia of Pain, works at the University Hospital of Siena and is a member of several national and international societies, such as the European Society of Pediatric Research, the Italian Society of Pediatrics and the Italian Society of Neonatology. He is a member of the directive board of the Italian Society of Neonatology’s study group on pain and analgesia. He owns some patents for medical instruments used in neonatal care and pain assessment. He has more than 300 publications, mainly in the field of fetal and neonatal pain assessment and therapy.  He has been appointed as an expert on animal fetal pain assessment by the European Community Authority for Foodsafety (EFSA).