Jinbo Xu & Sheng Wang 
Protein Homology Detection Through Alignment of Markov Random Fields [PDF ebook] 
Using MRFalign

Stöd

This work covers sequence-based protein homology detection, a fundamental and challenging bioinformatics problem with a variety of real-world applications. The text first surveys a few popular homology detection methods, such as Position-Specific Scoring Matrix (PSSM) and Hidden Markov Model (HMM) based methods, and then describes a novel Markov Random Fields (MRF) based method developed by the authors. MRF-based methods are much more sensitive than HMM- and PSSM-based methods for remote homolog detection and fold recognition, as MRFs can model long-range residue-residue interaction. The text also describes the installation, usage and result interpretation of programs implementing the MRF-based method.

€53.49
Betalningsmetoder

Innehållsförteckning

Introduction.- Method.- Software.- Experiments and Results.- Conclusion.

Köp den här e-boken och få 1 till GRATIS!
Språk Engelska ● Formatera PDF ● Sidor 51 ● ISBN 9783319149141 ● Filstorlek 2.8 MB ● Utgivare Springer International Publishing ● Stad Cham ● Land CH ● Publicerad 2015 ● Nedladdningsbara 24 månader ● Valuta EUR ● ID 5234167 ● Kopieringsskydd Social DRM

Fler e-böcker från samma författare (r) / Redaktör

940 E-böcker i denna kategori