Case study rich, this volume advances our understanding of the significance of ’the city’ in global governance. The editors call for innovation in international relations theory with case studies that add breadth to theorizing the role sub-national political actors play in global affairs. Each of the eight case studies demonstrates different intersections between the local and the global and how these intersections alter the conditions resulting from globalization processes. The case studies do so by focusing on one of three sub-themes: the diverse ways in which cities and sub-national regions impact nation-state foreign policy; the various dimensions of urban imbrications in global environmental politics; or the multiple methods and standards used to measure the global roles of cities.