Practical guidance based on expert experience and evidence for developing management strategies for vitiligo
This complete guide to vitiligo provides a full appraisal of strategy for the treatment of this autoimmune disease that affects 1-2% of the world’s population. It addresses all aspects of vitiligo, covering the science, medical and surgical therapies, and the psychological evaluations and approaches based on the proper understanding of the causes and classification of a particular case.
Management of vitiligo is challenging and requires a multipronged approach. Vitiligo: Medical and Surgical Management is a comprehensive, timely, state-of-the-art resource that will help those involved with affected patients better understand and treat this disease, which takes its toll on the mental wellness of those afflicted by it. It takes an evidenced-based approach to the disease’s treatment; provides an overview of the surgical management; covers tissue and cellular grafting; and more.
* Thoroughly guides those involved in the clinical aspects of vitiligo
* Aids diagnosis and classification of severity
* Balances evidence and experience
* Compiled by world-leading expert editors
Comprehensive in nature, Vitiligo: Medical and Surgical Management contains a strong practical element, and is a welcome go-to source for practicing dermatologists and those training to become a dermatologist.
Innehållsförteckning
Table of Contents
List of Contributors
1 Introduction
2 Melanocyte and melanogenesis: Applied anatomy and physiology
3 Epidemiology of Vitiligo
4 Pathogenesis of vitiligo
5 Understanding the mechanisms of repigmentation in vitiligo
6 Classification and Clinical Features of vitiligo
7 Outcome Measures for Vitiligo
8 Evaluation and treatment of the psychosocial burden of vitiligo
9 Patient support, education and compliance
10 Goals of Vitiligo Treatment, and Evidence Based Practice Guidelines for Medical and Surgical Management
11 The concept of stability of vitiligo and stabilization therapies
12 Narrowband Ultraviolet B Phototherapy in Vitiligo
13 UVA-based Phototherapy: PUVA, PUVA-sol, UVA1 phototherapy
14 Immunomodulators and immunosuppressives in Vitiligo
15 Topical Glucocorticoids, Topical Calcineurin Inhibitors and Topical Vitamin D3 Analogues
16 Targeted Phototherapy in Vitiligo
17 OTHER THERAPIES IN VITILIGO
18 Biologic therapies for vitiligo
19 Evidence toward integrated management of Vitiligo combining Ayurveda and Homeopathy with Modern Dermatology
20 History and chronology of development of surgical therapies for vitiligo
21 Patient selection, pre and postoperative information in surgical therapies for vitiligo
22 Classification of surgical therapies for vitiligo
23 Minigrafting for vitiligo
24 Suction blister epidermal grafting
25 Thin and ultra-thin skin grafts for vitiligo
26 Treatment of leukoderma by transplantation of ultra-thin epidermal sheets
27 Surgical management of leukotrichia
28 Mesh grafting in vitiligo
29 Smash Grafting
30 Therapeutic Needling and Needling Micrografting
31 Complications and limitations of melanocyte transplantation
32 Treatment of leukoderma by transplantation of basal cell layer suspension
33 Non cultured extracted follicle outer root sheath cell suspension transplantation
34 Long term results of non cultured epidermal cellular grafting in vitiligo
35 Simplified Non-Cultured Cellular Grafting
36 Novel methods of preparing epidermal cell suspension for transplantation in vitiligo
37 Setting up a tissue culture laboratory
38 Treatment of leukoderma by transplantation of cultured autologous melanocytes
39 Transplantation of in-vitro cultured epithelial grafts for vitiligo and piebaldism
40 Application of lasers for abrasion in transplantation procedures for vitiligo
41 Cell delivery on recipient skin
42 Safety concerns in transplantation of in vitro cultured cellular grafts
43 Surgical management of lip vitiligo, eyelids and genitals
44 Surgical management of acral vitiligo
45 Surgical management of leukotrichia
46 Surgical treatments of leukodermas other than vitiligo vulgaris
47 Ethnic issues in management and Sun protection
48 Management Issues for Vitiligo in Children and Pregnant Women
49 Combination treatments for Vitiligo
50 Micropigmentation
51 CAMOUFLAGE IN VITILIGO
52 Depigmentation treatment for vitiligo: bleaching cream, laser and cryotherapy
53 Future directions in medical and surgical management of vitiligo
54 Informed consent
Om författaren
About the Editors
Somesh Gupta, MD, DNB, MNAMS, Professor, Department of Dermatology & Venereology, All India Institute of Medical Sciences, New Delhi, India
Mats J. Olsson, MD, Ph D, CEO, Park Cell AB and President, International Vitiligo Center, Uppsala, Sweden
Davinder Parsad, MD, Professor, Department of Dermatology, Venereology & Leprology, Postgraduate Institute of Medical Education & Research, Chandigarh, India
Henry W. Lim, MD, Chair Emeritus, Department of Dermatology and Senior Vice President for Academic Affairs, Henry Ford Health System. Past President, American Academy of Dermatology, Detroit, USA
Nanja van Geel, MD, Ph D, Professor, Department of Dermatology, Ghent University Hospital, Ghent, Belgium
Amit G. Pandya, MD, Professor, Department of Dermatology, University of Texas, Southwestern Medical Center, Dallas, USA
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