The era of therapeutic nihilism in dementia has ended, with the
emergence of agents for symptomatic treatment, those that delay the
course of the disease or prevent the onset of dementia, and new
methods to manage symptoms. With the expansion of therapies, there
is a clear danger of being overwhelmed by the volume of data.
This book is designed to collect this information, distil what
is relevant and reliable, and present it in a format that is useful
to clinicians who manage and treat people with dementia. The book
is designed to bring together the latest, best and practical
evidence on all aspects of management, from diagnosis and therapy
to social and ethical considerations.
The editors are all dynamic clinicians involved in the care of
patients with dementia and the evaluation of therapies. Two of the
editors are the leaders of the Cochrane Collaboration for the
examination of therapies for dementia.
There are no other books that take such a practical and
problem-oriented or approach to the diagnosis and management of
dementia. Furthermore none but this can be described as truely
evidence-based.
Innehållsförteckning
SECTION I : Evidence-based Methods in Dementia.
Introduction.
Finding the evidence.
Critical Appraisal.
Evidence-based Etiology and Harm.
Evidence-based Diagnosis.
Evidence-based Prognosis.
Evidence-based Interventions.
Evidence-based Systematic Reviews and Meta-analyses.
Evidence-based Guidelines.
Evidence-based Economic Evaluation.
Accessing and Using the Best Evidence Efficiently in
Dementia.
Evidence-based Audit: Evaluating Implementation.
SECTION II : Diagnosis.
Introduction Practice Guidelines.
Reaching a Diagnosis of Dementia.
Reaching a Diagnosis of Dementia Subtype Conclusions.
SECTION III : Background Facts.
Historical Evolution of the Concept of Dementia: a Systematic
Review From 2000 BC to 2000 AD.
Alzheimer’s Disease.
Vascular Dementia.
Lewy Body Dementia.
Frontotemporal Lobar Atrophies: The Pick Complex.
Other Important Dementias.
Reversible or Arrestable Dementias.
Mild Cognitive Impairment.
SECTION IV: Overview of Treatment and Management.
Aims of Treatment.
Criteria for Clinical Decisions.
Clinical Decisions in Practice.
Delivering an Integrated Treatment Plan.
What is the Evidence that a Dementia Treatment Works?.
Non-pharmacological Techniques.
Drugs in Development and Experimental Approaches.
SECTION V: Therapies for Cognitive Symptoms, Disease
Modification and Prevention.
Introduction to Specific Therapies for Cognitive Symptoms or
Modifying Disease Prognosis.
Treatment of Alzheimer’s Disease (With or Without
Cerebrovascular disease).
Treatment of Vascular Dementia.
Treatment of Lewy Body Dementia.
Treatment of Reversible or Arrestable Dementias.
Treatment of Age-associated Memory Impairment.
Prevention of Dementia.
SECTION VI: Treating Non-cognitive Problems.
VI.A: A Problem-oriented Approach to Common Psychiatric
Problems.
Introduction.
Classes of Psychotropics – Overview of Evidence from Clinical
Trials.
Problems.
Summary, Practical Recommendations and Opinions.
VI.B: A Problem-oriented Approach to Common Medical
Problems.
Common Medical Problems.
SECTION VII: Social, Ethical and Health Services
Issues.
Social and Ethical Issues.
Driving.
Care-giver Interventions.
Genetic Counseling.
Nursing Home Care for Patients with Dementia.
Organisation of Care.
Memory Clinics – a Guide to Implementation and Evaluation.
Health Economics.
APPENDIX 1: Diagnostic Criteria for Common Dementias.
APPENDIX 2: Dementia Rating Scales.
APPENDIX 3: National Alzheimer’s Disease and Dementia
Associations and Societies.
Om författaren
Nawab Qizilbash is the editor of Evidence-based Dementia Practice, published by Wiley.
Lon S. Schneider is the editor of Evidence-based Dementia Practice, published by Wiley.
Henry Brodaty is the editor of Evidence-based Dementia Practice, published by Wiley.
Pierre Tariot is the editor of Evidence-based Dementia Practice, published by Wiley.
Jeffrey Kaye is the editor of Evidence-based Dementia Practice, published by Wiley.
Helena Chui is the editor of Evidence-based Dementia Practice, published by Wiley.
Timo Erkinjuntti is the editor of Evidence-based Dementia Practice, published by Wiley.
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