The definitive guide to surgical management of epilepsy in pediatric patients
This fully revised and updated second edition of Pediatric Epilepsy Surgery, edited by internationally renowned pediatric neurosurgeons and epilepsy surgery experts Oğuz Çataltepe and George Jallo, fills a void in the literature, encompassing the full spectrum of topics related to the surgical treatment of intractable epilepsy and seizures in children. The prodigiously illustrated book and its accompanying videos feature contributions from distinguished specialists in several different countries across a wide range of disciplines.
From epidemiology, genetics, pathology, preoperative electrophysiological assessment and neuroimaging to state-of-the-art surgical approaches, this remarkable resource covers the full depth and breadth of surgical management of pediatric epilepsy. Topics include awake anesthesia, intracranial stimulation and mapping techniques, temporal and extratemporal epilepsy surgery techniques, insular, multilobar and hemispheric surgery approaches, and diverse disconnection, neuromodulation, and ablative procedures. Insights are provided on postoperative issues including seizure control, neuropsychological and psychosocial outcomes, surgical failure and re-operation, and much more.
Key Features
- A review of topographic anatomy of the cerebral cortex and white matter with numerous illustrations provides enhanced understanding of eloquent anatomy.
- Discussion of cutting-edge techniques such as stereo-electroencephalography, multi-modality imaging and tractography, endoscopic and laser ablation approaches in hypothalamic hamartomas, peri-insular quadrantotomy, and various hemispherotomy approaches.
- Overview of common cortical stimulation and mapping techniques including magnetic and electrical stimulation modalities, functional MRI, and the WADA test.
- 13 videos demonstrate sei
Innehållsförteckning
<p><strong>Part I. Introduction to Epilepsy in Children</strong><br>1 Basic Considerations of Pediatric Epilepsy Surgery<br>2 A Historical Review of Epilepsy Surgery and Its Application in Children<br>3 Epidemiology of Intractable Epilepsy in Children<br>4 Genetics in Epilepsy Surgery<br>5 Surgical Neuropathology of Pediatric Epilepsy<br>6 Epilepsy and Brain Plasticity<br>7 Effects of Seizures and Their Comorbidities on the Developing Brain<br>8 Ethical Considerations in Pediatric Epilepsy Surgery<br>9 Infantile and Childhood-Onset Catastrophic Epilepsy Syndromes<br>10 Epilepsy Surgery for Congenital or Early Brain Lesions<br><strong>Part II. Preoperative Assessment</strong><br><strong><em>Section IIa. Preoperative Clinical and Neuropsychological Assessment</em></strong><br>11 Intractable Epilepsy in Children and Selection of Surgical Candidates<br>12 Clinical Semiology in Preoperative Assessment<br>13 Preoperative Neuropsychological and Cognitive Assessment<br><strong><em>Section IIb. Preoperative Electrophysiological Assessment</em></strong><br>14 Electroencephalography and Noninvasive Electrophysiological Assessment<br>15 Invasive Electrophysiological Monitoring<br>16 Extra- and Intraoperative Electrocortical Stimulation<br>17 Stereoelectroencephalography<br>18 Magnetoencephalography<br><strong><em>Section IIc. Preoperative Neuroimaging</em></strong><br>19 Structural Brain Imaging in Pediatric Epilepsy<br>20 Functional Magnetic Resonance Imaging in Pediatric Epilepsy Surgery<br>21 Application of Positron Emission Tomography and Single-Photon Emission Computed Tomography in Pediatric Epilepsy Surgery<br>22 Multimodality Imaging and Coregistration<br><strong>Part III. Surgical Anatomy and Mapping Techniques</strong><br>23 Cerebral Cortex: Embryological Development and Topographical Anatomy<br>24 Tractographic Anatomy of White Matter<br>25 Localization of Motor Cortex and Subcortical Pathways Using Functional Magnetic Resonance Imaging and Diffusion Tensor Imaging<br>26 The Wada Test: Lateralization of Language and Memory<br>27 Language Lateralization and Localization: Functional Magnetic Resonance Imaging<br>28 Localization of Eloquent Cortex and White Matter Tracts Under General Anesthesia<br>29 Cortical Stimulation and Mapping<br>30 Subcortical Mapping During Intracranial Surgery in Children<br><strong>Part IV. Surgical Treatment of Epilepsy</strong><br><strong><em>Section IVa. Anesthesia</em></strong><br>31 Anesthetic Considerations and Postoperative Intensive Care Unit Care in Pediatric Epilepsy Surgery<br>32 Pediatric Awake Craniotomy<br><strong><em>Section IVb. Intracranial Electrode Placement for Invasive Monitoring</em></strong><br>33 Implantation of Strip, Grid, and Depth Electrodes for Invasive Electrophysiological Monitoring<br>34 Stereoelectroencephalography in Children: Methodology and Surgical Technique<br><strong><em>Section IVc. Temporal Lobe Epilepsy and Surgical Approaches</em></strong><br>35 Mesial Temporal Sclerosis in Pediatric Epilepsy<br>36 Anteromesial Temporal Lobectomy<br>37 Selective Amygdalohippocampectomy<br>38 Surgical Management of Lesional Temporal Lobe Epilepsy<br>39 Surgical Management of MRI-Negative Temporal Lobe Epilepsy<br><strong><em>Section IVd. Extratemporal Lobe Epilepsy and Surgical Approaches</em></strong><br>40 Surgical Management of Insular–Opercular Epilepsy in Children<br>41 Focal Cortical Dysplasia: Histopathology, Neuroimaging, and Electroclinical Presentation<br>42 Surgical Approaches in Cortical Dysplasia<br>43 Tuberous Sclerosis Complex<br>44 Resective Epilepsy Surgery for Tuberous Sclerosis Complex<br>45 Extratemporal Resection and Staged Epilepsy Surgery in Children<br>46 Supplementary Sensorimotor Area Surgery<br>47 Rolandic Cortex Surgery<br>48 Anterior Peri-insular Quadrantotomy<br>49 Posterior Peri-insular Quadrantotomy<br>50 Tailored Extratemporal Resection in Children with Epilepsy<br>51 Surgical Management of MRI-Negative Extratemporal Lobe Epilepsy<br>52 Surgical Management of Hypothalamic Hamartomas<br><strong><em>Section IVe. Hemispheric Surgery Techniques</em></strong><br>53 Hemispherectomy and Hemispherotomy Techniques in Pediatric Epilepsy Surgery<br>54 Multifocal Epilepsy and Multilobar Resections<br>55 Anatomical Hemispherectomy<br>56 Hemidecortication for Intractable Epilepsy<br>57 Functional Hemispherectomy at the University of California, Los Angeles<br>58 Transsylvian Hemispheric Deafferentation<br>59 Vertical Parasagittal Hemispherotomy<br>60 Peri-insular Hemispherotomy<br>61 Endoscope-Assisted Hemispherotomy<br><strong><em>Section IVf. Other Disconnective Procedures</em></strong><br>62 Corpus Callosotomy<br>63 Endoscope-Assisted Corpus Callosotomy with Anterior, Hippocampal, and Posterior Commissurotomy<br>64 Endoscopic Disconnection of Hypothalamic Hamartomas<br>65 Multiple Subpial Transections in Children with Refractory Epilepsy<br>66 Hippocampal Subpial Transection<br><strong><em>Section IVg. Neuromodulation Procedures</em></strong><br>67 Vagal Nerve Stimulation<br>68 Cortical and Deep Brain Stimulation<br><strong><em>Section IVh. Radiosurgery and Ablative Procedures</em></strong><br>69 Radiosurgical Treatment for Epilepsy<br>70 Stereotactic Laser Ablation for Hypothalamic Hamartomas<br>71 MRI-Guided Laser Thermal Therapy in Pediatric Epilepsy Surgery<br><strong>Part V. Postoperative Course and Outcome</strong><br>72 Surgical Failure and Reoperation<br>73 Postoperative Seizure Control<br>74 Postoperative Neuropsychological and Psychosocial Outcome</p>
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