The title of this book derives from C. Wright Mills’ classic The Sociological Imagination (Penguin, 1970), in which he sees the essential project of social science as the use of the imagination to ’grasp history and biography and the relations between the two in society’. This enables the social scientist to ’range from the most impersonal and remote transformations to the most intimate features of the human self’. Another of Mills’ concerns was the relationship between ’the personal troubles of the milieu’ and ’the public issues of social structure’ and these are most acutely illustrated in human genetics, the most personal of the new technologies. The chapters in this volume address these issues through discussions of choice and informed decision-making, risks and hazards, the economic and political organization of new technology, and the public as well as the scientist’s understanding of science. The methods used range from detailed ethnographies, through deconstruction’s of text and action, to surveys and interviews.