This book helps readers move from fundamental organic chemistry principles to a deeper understanding of reaction mechanisms. It directly relates sophisticated mechanistic theories to synthetic and biological applications and is a practical, student-friendly textbook.
* Presents material in a student-friendly way by beginning each chapter with a brief review of basic organic chemistry, followed by in-depth discussion of certain mechanisms
* Includes end-of-chapter questions in the book and offers an online solutions manual along with Power Point lecture slides for adopting instructors
* Adds more examples of biological applications appealing to the fundamental organic mechanisms
Innehållsförteckning
Preface xv
First Edition Preface xvii
1 Fundamental Principles 1
2 The Aliphatic C-H Bond Functionalization 53
3 Functionalization of the Alkene C=C Bond by Electrophilic Additions 95
4 Functionalization of the Alkene C=C Bond by Cycloaddition Reactions 143
5 The Aromatic C-H Bond Functionalization and Related Reactions 199
6 Nucleophilic Substitutions on sp³-Hybridized Carbons: Functional Group Transformations 257
7 Eliminations 317
8 Nucleophilic Additions and Substitutions on Carbonyl Groups 367
9 Reactivity of the alpha-Hydrogen to Carbonyl Groups 417
10 Rearrangements 457
Index 493
Om författaren
XIAOPING SUN, PHD, is Professor of Chemistry at the University of Charleston, Charleston, West Virginia. He has twenty years of experience teaching organic chemistry, biochemistry, and inorganic chemistry.
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