Photodynamic therapy (PDT) utilizes photosensitizers (PS) together with irradiating light of specific wavelength interacting with oxygen to generate cytotoxic reactive oxygen species, in particular singlet oxygen, which has been approved for the clinical treatments of several malignant and non-malignant pathologies. Most recently, enhanced PDT was successfully achieved by using new light sources (i.e., light-emitting diode), novel functional nano-PSs, oxygen supply and synergistic therapy. In addition, PDT was widely used in the fields of antibacterial, antimicrobial and antibiofilm activities. The aim of this book is to highlight innovations in the fundamental mechanisms of enhanced PDT for clinical applications, and 20 papers published in the Journal of Innovative Optical Health Sciences during 2020–2023 were selected.
Contents:
- Developments in Light Sources and Emission Quantifications:
- Implementation and Uniformity Calibration of LED Array for Photodynamic Therapy
- A Portable Illumination Device for Photodynamic Therapy of the Oral Cavity
- Novel Intense Pulsed Light-Photodynamic Therapy Strategy in the Treatment of Facial Actinic Keratoses Concomitant With Rosacea
- Development of New Photosensitizers and Photosensitizer Monitoring or Quantification:
- Development of a Hydrogen Peroxide-Responsive and Oxygen-Carrying Nanoemulsion for Photodynamic Therapy Against Hypoxic Tumors Using Phase Inversion Composition Method
- Binary Organic Nanoparticles with Enhanced Reactive Oxygen Species Generation Capability for Photodynamic Therapy
- The Application of Inorganic Optical Nanoprobes in Bacterial Infection
- Orthogonal Aza-BODIPY–BODIPY Dyad as Heavy-Atom Free Photosensitizer for Photo-Initiated Antibacterial Therapy
- Meso-Substituted Cationic 3- and 4-N-Pyridylporphyrins and their Zn(II) Derivatives for Antibacterial Photodynamic Therapy
- Multi-Variety and Multi-Manufacturer Drug Identification Based on Near-Infrared Spectroscopy and Recurrent Neural Network
- A ‘Donor–Acceptor’ Structured Semiconductor Polymer for Near Infrared Fluorescence Imaging Guided Photodynamic Therapy
- A Novel Bodipy-Based Nano-Photosensitizer with Aggregation-Induced Emission for Cancer Photodynamic Therapy
- Photoswitchable Semiconducting Polymer Dots with Photosensitizer Molecule and Photochromic Molecule Loading for Photodynamic Cancer Therapy
- Cerium-Based Nanoparticles for Cancer Photodynamic Therapy
- Ultrasmall p H-Responsive Silicon Phthalocyanine Micelle for Selective Photodynamic Therapy Against Tumor
- PDT Tissue Response Monitoring New Developments for PDT and Potentially for PDT:
- Three-Dimensional Imaging of Spatio-Temporal Dynamics of Small Blood Capillary Network in the Cortex Based on Optical Coherence Tomography: A Review
- Structured Illumination Microscopy Based on Asymmetric Three-Beam Interference
- Varying of Up-Conversion Nanoparticles Luminescence from the Muscle Tissue Depth During The Compression
- High-Speed All-Optic Optical Coherence Tomography and Photoacoustic Microscopy Dual-Modal System for Microcirculation Evaluation
- Monitoring of Time-Resolved Singlet Oxygen Luminescence at 1270 nm by an Optical Fiber Detection System
- Application and Development of Fluorescence Probes in MINFLUX Nanoscopy
Readership: Advanced undergraduate and graduate students, researchers and practitioners in the fields of photodynamic therapy and photonic theranostics.
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