This work encapsulates the uses of mi RNA across stem cells, developmental biology, tissue injury and tissue regeneration. In particular contributors provide focused coverage of methodologies, intervention and tissue engineering. Regulating virtually all biological processes, the genome’s 1048 encoded micro RNAs appear to hold considerable promise for the potential repair and regeneration of tissues and organs in future therapies. In this work, 50 experts address key topics of this fast-emerging field. Concisely summarizing and evaluating key findings emerging from fundamental research into translational application, they point to the current and future significance of clinical research in the mi RNA area. Coverage encompasses all major aspects of fundamental stem cell and developmental biology, including the uses of mi RNA across repair and regeneration, and special coverage of methodologies and interventions as they point towards organ and tissue engineering- Multi-colour text layout with 150 colour figures to illustrate important findings- Take home messages encapsulate key lessons throughout text- Short chapters offer focused discussion and clear ‘voice’