An extensive update of the classic reference on organic reactions
in water
Published almost a decade ago, the first edition has served as the
guide for research in this burgeoning field. Due to the cost,
safety, efficiency, and environmental friendliness of water as a
solvent, there are many new applications in industry and academic
laboratories. More than forty percent of this extensively updated
second edition covers new reactions. For ease of reference, it is
organized by functional groups. A core reference, Comprehensive
Organic Reactions in Aqueous Media, Second Edition:
* Provides the most comprehensive coverage of aqueous
organicreactions available
* Covers the basic principles and theory and progresses to
applications
* Includes alkanes, alkenes, aromatics, electrophilic
substitutions, carbonyls, alpha, beta-unsaturated carbonyls,
carbon-nitrogen bonds, organic halides, pericyclic reactions,
photochemical reactions, click chemistry, and multi-step
syntheses?
* Provides examples of applications in industry
This is the premier reference for chemists and chemical engineers
in industry or research, as well as for students in advanced-level
courses.
สารบัญ
PREFACE TO THE SECOND EDITION.
1. INTRODUCTION.
1.1 The Structure and Forms of Water.
1.2 Properties of Water.
1.3 Solvation.
1.4 Hydrophobic Effect.
1.5 Salt Effect.
1.6 Water Under Extreme Conditions.
References.
2. ALKANES.
2.1 Oxygenation of Alkanes.
2.2 Halogenation of Alkanes.
2.3 Formation of Carbon-Carbon Bonds.
2.4 D/H Exchange of Alkanes in Water.
References.
3. ALKENES.
3.1 Reduction.
3.2 Electrophilic Additions.
3.3 Radical Reactions of Alkenes.
3.4 Carbene Reactions.
3.5 Alkene Isomerization.
3.6 Transition-Metal Catalyzed C-C Formation
Reactions.
3.7 Olefin Metathesis.
3.8 Reaction of Allylic C-H Bond.
4. ALKYNES.
4.1 Reaction of Terminal Alkynes.
4.2 Additions of C identical to C bonds.
4.3 Transition-Metal Catalyzed Cycloadditions.
4.4 Other Reactions.
References.
5. ALCOHOLS, PHENOLS, ETHERS, THIOLS, AND THIOETHERS.
5.1 Oxidation of Alcohols.
5.2 Substitutions/Elimination.
5.3 Addition of Alcohols, Phenols, and Thiols to Alkene and
Alkyne Bonds.
5.4 Addition of Alcohols to C=O Bonds: Esterification and Acetal
Formations.
5.5 Reaction of Ethers and Cyclic Ethers.
5.6 Reaction of Sulfur Compounds.
6. ORGANIC HALIDES.
6.1 General.
6.2 Reduction.
6.3 Elimination Reactions.
6.4 Nucleophilic Substitutions.
6.5 Reductive Coupling.
6.6 Carbonylation of Organic Halides.
6.7 Transition-Metal Catalyzed Coupling Reactions.
References.
7. AROMATIC COMPOUNDS.
7.1 General.
7.2 Substitution Reactions.
7.3 Oxidation Reactions.
7.4 Reductions.
References.
8. ALDEHDYE AND KETONES.
8.1 Reduction.
8.2 Oxidation.
8.3 Nucleophilic Addition: C-C Bond Formation.
8.4 Pinacol Coupling.
8.5 Other Reactions (Halogenation and Oxidation of
alpha-H).
References.
9. CARBOXYLIC ACIDS AND DERIVATIVES.
9.1 General.
9.2 Carboxylic Acids.
9.3 Carboxylic Acid Derivatives.
References.
10. CONJUGATED CARBONYL COMPOUNDS.
10.1 Reduction.
10.2 Epoxidation, Dihydroxylation, Hydroxyamination.
10.3 Conjugate Addition: Heteroatom.
10.4 C-C Bond Formation.
10.5 Other Reactions.
References.
11. NITROGEN COMPOUNDS.
11.1 Amines.
11.2 Imines.
11.3 Diazo Compounds.
11.4 Azides.
11.5 Nitro Compounds.
References.
12. PERICYCLIC REACTIONS.
12.1 Introduction.
12.2 Diels-Alder Reactions.
12.3 Sigmatropic Rearrangements.
12.4 Photochemical Cycloaddition Reactions.
References.
INDEX.
เกี่ยวกับผู้แต่ง
Chao-Jun Li, Ph D, is Professor at Mc Gill University in
Canada. Professor Li began teaching at Tulane University in 1994
and received an NSF CAREER Award for work done from
1998-2002, the Outstanding Young Oversea Scientist Award from
the NSFC in 2001, and the U.S. Presidential Green Chemistry
Challenge Award in Academia for 2001. Dr. Li moved to Mc Gill
University in 2003 and received a Canada Research Chair in Green
Chemistry (Tier I). He coauthored the popular first edition of
Organic Reactions in Aqueous Media (Wiley).
Tak-Hang Chan, Ph D, is Professor Emeritus at Mc Gill
University in Canada and Chair Professor of Organic Chemistry at
the Hong Kong Polytechnic University in Hong Kong. In 1993,
Professor Chan received the prestigious R.U. Lemieux Award of the
Canadian Society of Chemistry. A pioneer in green chemistry, he is
a Fellow of the Royal Society of Canada and holds Honorary
Professorships at Academia Sinica, Peking University, and Lanzhou
University. He was coauthor of the first edition.