Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular basis of drug action, both applied and experimental.Conjugation reactions have long been associated with the detoxification of xenobiotics. Recent studies suggest that Phase II reactions are an important mechanism for the bioactivation of xenobiotics.This special volume of Advances in Pharmacology features a two-color dust jacket.Summarizes the most recent information on:- Xenobiotic conjugation- Drug toxicity, hypersensitivity, and targeting- Chemical carcinogenesis- Glutathione-, sulfate conjugate-, and glucuranide conjugate-dependent toxicity- Bioactivation and bioconversion