This book presents topical research in the study of the composition, functions and pathology of endothelium and epithelium. Topics discussed include the pathophysiology of endothelium; the role of epithelial innate immunity in inflammatory diseases; morphofunctional characteristic features of statis endothelium and dynamic epithelial cell populations; changes of respiratory epithelium in bronchial asthma; interleukin-6 (IL6) signaling and its role in the development of cardiovascular disease; endothelium-dependent effects of heat shock on vasomotor tone; the Gasdermin Superfamily functioning in epithelial cells and tight junctions in upper airway epithelium.