Despite of the enormous potential, only a minor fraction of globes living species has ever been tested for any bioactivity. For instance, approximately only 10% of all existing plant species has been assayed, and in the case of microbes the value is even lower. Natural products have a range of potential applications, including pharmaceuticals, dietary supplements, and controls agents for crop pests and diseases. Extracts and bio molecules with promising activity are unscrupulously screened for efficacy to determine if these products have a potential for commercial development.