This collection invites readers to reposition Esposito’s thought and explore the interdisciplinarity and unique methodology of his whole corpus. It addresses Esposito’s long-standing engagement with early modern philosophy, philosophy of biology, biopolitics, and the impolitical and the impersonal, together with his significant dialogues with contemporary philosophers like Gilles Deleuze, Jacques Derrida, Simone Weil, Jean-Luc Nancy and Maurice Blanchot. A new essay by Esposito himself reveals the importance of philosophical sources and ideas that condition his thinking, especially outside and beyond the dominant biopolitical interpretative framework that has come to mark his reception in the English-speaking world.