Koichi Furukawa & Minoru Fukuda 
Glycosignals in Cancer [PDF ebook] 
Molecular Assembly and Recognition

Destek

This book, now in an extensively revised second edition, provides a comprehensive summary of the latest knowledge regarding glycosignals and a thorough analysis of their involvement in not only cancers but also other refractory conditions such as chronic inflammatory disorders. Many relevant topics are covered, including the search for novel tumor epitopes related to carbohydrates, the assembly of glycoconjugates, the modulation of signaling pathways by glycosylation, and interactions between complex carbohydrates and their recognition molecules. The role of various research approaches, for example advanced mass spectrometry, high-resolution imaging, and bioinformatics, is closely examined, and the results of novel therapeutic trials targeting glycosignals are discussed. The book will be essential reading for students and young researchers with an interest in glycoscience. In presenting new results and approaches and identifying areas for future research, it will also be of benefitfor specialists in the field.




€149.79
Ödeme metodları

İçerik tablosu

Part I. Search for novel tumor epitopes related to carbohydrates.- Chapter 1.1. The ganglioside structures: chemistry and biochemistry.- Chapter 1.2. Fucosylated proteins as cancer biomarkers.- Part II. Assembly of glycoconjugates.- Chapter 2.1. Siglec-7 and synthetic sialylpolymer.- Chapter 2.2. Role of Sialyl-Tn antigen in Cancer Metastasis.- Chapter 2.3. Insights into the Role of Chondroitin Sulfate in Cancer.- Part III. Signaling pathways modulated by glycosylation.- Chapter 3.1. Significance of FUT8in pancreatic cancer and others.- Chapter 3.2. Effects of Bullfrog sialic acid-binding lectin in cancer cells.- Part IV. Interaction between carbohydrate and carbohydrate-recognizing molecules.- Chapter 4.1. Opposite functions of mono- and disialylated glycosphingolipids on the membrane of cancer cells.- Chapter 4.2. Tumor progression through interaction of mucins with lectins and subsequent signal transduction.- Part V. Clinical trials targeting glycosignals.- Chapter 5.1. Immunotherapy of Neuroblastoma Targeting GD2 and Beyond.





Yazar hakkında


Koichi Furukawa


College of Life and Health Sciences,  Chubu University, Japan





Minoru Fukuda


Cancer Research Center, Standford-Burnham Medical Research Institute La Jolla, CA, USA
Bu e-kitabı satın alın ve 1 tane daha ÜCRETSİZ kazanın!
Dil İngilizce ● Biçim PDF ● Sayfalar 238 ● ISBN 9789811977329 ● Dosya boyutu 8.9 MB ● Editör Koichi Furukawa & Minoru Fukuda ● Yayımcı Springer Nature Singapore ● Kent Singapore ● Ülke SG ● Yayınlanan 2023 ● Baskı 2 ● İndirilebilir 24 aylar ● Döviz EUR ● Kimlik 8881062 ● Kopya koruma Sosyal DRM

Aynı yazardan daha fazla e-kitap / Editör

10.834 Bu kategorideki e-kitaplar