Advances in Medicine and Biology. Volume 158 reviews the evolution of the network-based approaches to understanding comorbidities. These approaches can reveal underlying molecular mechanisms by identifying perturbations in shared proteins or protein-protein interactions as the cause of comorbidity. Subsequently, the authors discuss radiculopathy, a painful condition in which conduction along a spinal nerve is blocked resulting in objective neurologic signs such as numbness or weakness or in compromised blood supply to a spinal nerve root, resulting in paresthesia. This collection also provides a practical reference for several aspects of blunt craniofacial trauma management, including clinical presentation recognition, the classification of injuries, and the indications for urgent interventions. 36 structures of VEGFR-2 are available in the protein data bank. In the penultimate chapter, a visual analysis is carried out for the identification of the conformation. 31 structures were present in the DFG-out conformation. The concluding chapter provides useful information about folate and its significant role in health maintenance and disease prevention, as well as dietary recommendations to researchers in basic sciences, public health, and clinical medicine.