The chapter “Calcium Signaling: From Basic to Bedside” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
İçerik tablosu
Preface.- Calcium signaling: from basics to bedside.- Measuring Ca2+ in living cells.- High-throughput fluorescence assays for Ion Channels and GPCRs.- Imaging Native Calcium Currents in Brain Slices.- Molecular diversity of plasma membrane Ca2+ transporting ATPases: their function under normal and pathological conditions.- A role for SERCA pumps in the neurobiology of neuropsychiatric and neurodegenerative disorders.- Cytoplasmic Calcium Buffering: An Integrative Crosstalk.- An update on calcium binding proteins.- Manuel Campos‐Toimil.- New insights in the IP3 receptor and its regulation.- Expression of the inositol 1, 4, 5-trisphosphate receptor and the ryanodine receptor Ca2+-release channels in the beta-cells and alpha- cells of the human islets of Langerhans.- Evolution of Excitation-Contraction Coupling.- Molecular Insights into Calcium Dependent Regulation of Ryanodine Receptor Calcium Release Channels.- Sarco-endoplasmic reticulum calcium release model based on changes in the luminal calcium content visualized from the luminal side.- Pyridine Nucleotide Metabolites and Calcium Release from Intracellular Stores.- Calcium Signaling in the Heart.- Molecular basis and regulation of store-operated calcium entry.- Structure and activation mechanisms of CRAC channels.- Canonical Transient Potential Receptor-3 Channels in Normal and Diseased Airway Smooth Muscle Cells.- Pathophysiological significance of store-operated calcium entry in cardiovascular and skeletal muscle disorders and angiogenesis.- Calcium signalling and the regulation of chemosensitivity in cancer cells: role of the Transient Receptor Potential channels.- Targeting Transient Receptor Potential Channels by micro RNAs drives tumor development and progression.- Calcium channels and Calcium-regulated channels in human red blood cells.- Regulation of multifunctional calcium/calmodulin stimulated protein kinases by molecular targeting.- Widespread roles of Ca MK-II in Developmental Pathways.- Readily releasable stores of calcium in neuronal endolysosomes: Physiological and pathophysiological relevance.- At the crossing of ER stress and MAMs: A key role of Sigma-1 receptor?- ER-mitochondria calcium transfer, organelle contacts and neurodegenerative diseases.- The Role of Mitochondrial Calcium Signaling in the Pathophysiology of Cancer Cells.- Calcium Signaling and Gene Expression.- Simulation Strategies for Calcium Microdomains and Calcium Noise.- A statistical view on calcium oscillations.- Calcium Regulation of Bacterial Virulence.- Ca2+ Signaling in Drosophila Photoreceptor Cells.- Calcium imaging in Drosophila melanogaster.- Calcium imaging in the zebrafish.- Stimulation-secretion coupling in the beta cells: from basic to bedside.- Calcium dynamics and synaptic plasticity.- Calcium signaling during brain aging and its influence on the hippocampal synaptic plasticity.- Calcium Signaling in Endothelial Colony Forming Cells in Health and Disease.- Sensing Extracellular Calcium – An Insight into the Structure and Function of the Calcium-Sensing Receptor (Ca SR).- Extracellular Ca2+ in bone marrow.- Calcium in Cell-Extracellular Matrix Interactions.- Index.