The two-volume set on C-1 Building Blocks in Organic Synthesis critically reviews the state of the art of a wide variety of reactions by which one carbon atom is added to an organic molecule, forming a C-C bond. In spite of the numerous classic reactions of this kind, there has been enormous progress in recent years, especially for those reactions involving catalytic methods. Introduction of substituted methyl groups is a major challenge and only very recently the first catalysts have been discovered that enable the introduction of fluoromethyl groups in aromatics.
İçerik tablosu
<p>1.1 Addition to Alkenes<br>1.1.1 Hydroformylation of Alkenes<br>1.1.2 Asymmetric Hydroformylation of Alkenes<br>1.1.3 Tandem Hydroformylation of Alkenes<br>1.1.4 Nonconventional Reaction Media: Hydroformylation, Carbonylation, and Hydroxycarbonylation of Alkenes<br>1.1.5 Hydroformylation of Alkenes: Industrial Applications<br>1.1.6 Carbonylation of Alkenes<br>1.1.7 Cyclopropanation of Alkenes with C-1<br>1.1.8 Addition of Carbon Dioxide to Alkenes and Other Unsaturated Hydrocarbons<br>1.1.9 Hydrocyanations of Alkenes<br>1.1.10 Stereoselective Conjugate Addition of Methyl and Cyanide<br>1.1.11 Enantioselective Conjugate Addition of Nitromethane<br>1.2 Addition to Alkynes<br>1.2.1 Carbonylation of Alkynes<br>1.3 Addition to Carbonyl Compounds and Derivatives<br>1.3.1 Stereoselective (Nucleophilic) Methylation of Ketones and Aldehydes<br>1.3.2 Cyanation of Ketones, Aldehydes, and Imines<br>1.3.3 Stereoselective Addition of Nitromethane</p>
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