This timely Handbook examines the rapidly expanding research area of digital platforms and business ecosystems in the context of manufacturing industries. Chapters analyze core topics such as business model transformation, ecosystem design and governance, offering an up-to-date overview of crucial research.Multidisciplinary in scope, the Handbook includes rigorously researched contributions from over 60 global experts from a variety of areas including management, computer science, and industrial engineering. Chapters explore a wealth of industry applications, bridging the previous research gap between the study of digital platforms and other prominent disciplines by proposing an integrated approach to manufacturing. Ultimately, this erudite Handbook emphasizes the superior resilience of ecosystem-based platforms in addressing any potential supply chain disruption.Scholars and students of business administration, economics and computer science will find this book to be of great benefit. Due to its practical scope, it will also be valuable for practitioners in management fields.