This book presents original results on the leading edge of computer science research. Chapter One discusses motion planning for robots with rigid bodies. Chapter Two provides an overview of handheld/mobile computing devices, pathology applications, social media in the context of pathology, and novel mobile-driven technologies like wearables and mixed reality tech, and discusses their potential impact in pathology. Chapter Three focuses on reliability and accessibility issues of a distributed cloud service based on Semi-Markov modeling. Chapter Four examines parallel dynamic programming for large-scale date applications. Chapter Five presents the ensemble of both texture and color features for reliable person re-identification. Chapter Six provides an overview of common techniques and commercial products used in tracking people and objects within indoor environments. Chapter Seven analyzes quadratic programming formulation for controlling the emissions of air pollution point sources.