Pharmacology in Veterinary Anesthesia and Analgesia
A concise yet comprehensive and usable pharmacological resource for veterinary practitioners
In Pharmacology in Veterinary Anesthesia and Analgesia, a team of distinguished veterinary practitioners delivers a singular and comprehensive text dedicated to anesthetic drug pharmacology and drug interactions related specifically to anesthetic drugs in a veterinary setting. This concise, easily navigable reference combines information scattered throughout the academic literature and covers mechanisms of action of commonly used drugs in commonly encountered species, drug interactions, and clinical uses of anesthetic drugs.
The volume explores drug metabolism, the effects of various drugs on organ systems, risks of adverse effects, as well as the impact of anesthesia on drugs, and the effects of drugs on anesthesia.
Readers will also find:
* A thorough introduction to pharmacokinetics, pharmacodynamics, and pharmacogenomics in veterinary anesthesia
* Comprehensive explorations of veterinary regulatory concerns associated with anesthesia and analgesia for food animals
* Practical discussions of alpha-2 agonists and antagonists, phenothiazines, butyrophenones, benzodiazepines, and opioid agonists and antagonists
* Fulsome treatments of local anesthetics, non-steroidal anti-inflammatory drugs, inhalants, and induction drugs
Perfect for veterinary anesthesiologists and criticalists, internists, and surgeons, Pharmacology in Veterinary Anesthesia and Analgesia will also earn a place in the libraries of private practitioners and veterinary technicians performing anesthesia as well as researchers using veterinary species as a model.
Table of Content
List of Contributors xxiv
Preface xxvi
1 Pharmacokinetics and Pharmacodynamics 1
Phillip Lerche and Jeffrey Lakritz
2 Pharmacogenetics in Veterinary Anesthesia and Analgesia 13
Jeffrey Lakritz
3 Veterinary Regulatory Concerns Associated with Anesthesia and Analgesia for Food Animals 31
Jeffrey Lakritz
4 alpha2 Receptor Agonists and Antagonists 36
Lydia Love
5 Phenothiazines and Butyrophenones 55
John A.E. Hubbell
6 Benzodiazepines 60
Sébastien Hyacinthe Bauquier
7 Opioid Agonists and Antagonists 75
Phillip Lerche
8 Barbiturates 96
Bonnie L. Hay Kraus
9 Induction Drugs 106
Jennifer E. Carter
10 Inhalant Anesthetic Agents 123
Phillip Lerche and Linda Barter
11 Non-Steroidal Anti-Inflammatory Drugs 138
Craig Willette
12 Local Anesthetics 164
Turi K. Aarnes
13 Anticholinergics 171
Phillip Lerche
14 CNS Stimulants 177
Caitlin Tearney
15 Centrally Acting Muscle Relaxants 183
Bonnie L. Hay Kraus
16 Neuromuscular Blocking Agents 202
Manuel Martin-Flores and Daniel M. Sakai
17 Anticholinesterase Drugs and Reversal of Neuromuscular Blockade 215
Manuel Martin-Flores and Daniel M. Sakai
18 Sympathomimetics and Vasopressin 221
Phillip Lerche
19 Antihypertensives 236
Gianluca Bini
20 Antiarrhythmic Therapies and Calcium Channel Blockers 252
Lance C. Visser
21 Peripheral Vasodilators 266
Martin Kennedy
22 Behavior Drugs 283
Erin Wendt-Hornickle
23 Adjunctive Analgesic Pharmaceuticals 303
Reza Seddighi
24 Diuretics 315
Andrew Claude
25 Antiepileptics 324
Laurie Cook and Ashley C. Hechler
26 Antihistamines 339
S. Bryce Dooley
27 Anti-nausea, Antacid, and Prokinetic Drugs 350
Phillip Lerche
28 Insulin 357
Phillip Lerche
29 Electrolytes 362
Teresa A. Burns
30 IV Fluids 370
Anusha Balakrishnan
31 Blood and Blood Products 382
Julien Guillaumin
Index 392
About the author
The Editors
Turi Aarnes, DVM, MS is Associate Professor at The Ohio State University College of Veterinary Medicine. She is a Diplomate of the American College of Veterinary Anesthesia and Analgesia.
Phillip Lerche, BVSc, Ph D is Professor – Clinical at The Ohio State University College of Veterinary Medicine. He is a Diplomate of the American College of Veterinary Anesthesia and Analgesia.
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