Age-related macular degeneration is the most common cause for the loss of central vision beyond the age of 50 in industrial nations. Triplication of the number of affected patients is expected over the next 25 years. Especially over the last years the standard of knowledge regarding etiology, risk factors, diagnostics and therapy of this retina illness has substantially grown – this will be covered in this up-to-date multi-authored work. Apart from epidemiologically and genetically identified risk factors both the various pathophysiological aspects including the role of the complement system and clinical manifestations including OCT and angiographic characteristics are clearly represented. Furthermore, the different therapeutic approaches are presented and discussed, including proven procedures such as intravitreal anti-VEGF therapy and seeing-aid systems, in addition to the latest and upcoming methods in the area of pharmacology. The volume is well-illustrated and tables and summaries complete the presentation.
Зміст
Pathophysiology: Epidemiology.- Genetics of AMD.- Aging of the Retina and Retinal Pigment Epithelium.- Complement System.- Current Concepts in AMD-Pathogenesis. Clinical Manifestations: Early AMD.- Neovascular AMD.- Geographic Atrophy. Diagnostics: Fluorescein- und ICG-Angiography.- Optical Coherence Tomography.- Microperimetry. Prophylaxis and Therapy: Nutritional Supplementation.- Laser Photocoagulation and Photodynamic Therapy.- Anti-VEGF-Therapy: Basic Information and Substances.- Anti-VEGF-Therapy: Results and Guidelines.- Combination Therapies for the Treatment of AMD.- Treatment Approaches for Dry Atrophy.- Surgical Therapy. Rehabilitation: Reading Ability.- Magnifying Visual Aids.
Про автора
Frank G. HOLZ is Professor of Ophthalmologic Surgery at the University of Bonn, Germany. He is author of many publication, for example within the series Essentials in Ophthalmology.
Daniel PAULEIKOFF is Professor of Ophthalmology at the St. Franziskus Hospital in Münster, Germany.
Richard F. SPAIDE, MD specializes in disease of the retina and vitreous. His particular interest includes retinal surgery, macular degeneration, macular holes, diabetic retinopathy. He is author of numerous books, for example within the Essential in Ophthalmology Series.
Alan C. BIRD is Professor at Moorfields Eye Hospital in London, UK
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