Sex matters! Are there differences between the sexes when it comes to brain function and the behaviours that result? This volume attempts to answer this fundamental question. If the answer is ‘yes’ then this should impact upon our approach to treating mental illness in humans, and to modelling it in animals, as we look for aetiological and pharmacological solutions.
Зміст
Preface.- Female rats are smarter than males: influence of test, oestrogen receptor subtypes and glutamate.- Differences in sexual behaviour in male and female rodents: role of serotonin.- Sex differences in the cholinergic system in rats: behavioural consequences.- Sex differences in response to stress and expression of depressive-like behaviours in the rat.- Females are more vulnerable to drug relapse, evidence from preclinical studies and role of ovarian hormones and estrogen receptors.- Genetics and sex differences: role of COMT.- Sex differences precipitating anorexia nervosa in females: A novel framework for targeting sex specific neurocircuits and behavior.- Gender differences in developmental disorders - biological causes and treatments.- The estrogen hypothesis of schizophrenia.- Sex and its impact on antidepressants.- Bipolar recurrences after childbirth and possible biological mechanisms.- Introduction to the interaction between gonadal steroids and the central nervous system.- Sex Differences and Hormonal Influences in Human Sensorimotor Gating: Implications for Schizophrenia.
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