Biotargets of Cancer in Current Clinical Practice presents an updated and reasoned review of the current status of knowledge concerning the major cancer types with a special focus on the current biomarkers, genes involved and the potential future targets of innovative therapies. The volume includes for each major cancer type, a comprehensive although concise discussion of epidemiology, affirmed and innovative biomarkers for diagnosis, and descriptions of the relevant genes for prognosis and (individualized) therapy through biotarget-specific new molecular treatments, with the latest information on the validation status of each novel biomarker. Individual chapters are dedicated to the major cancer types, plus a special chapter on metastasis. The present debate on patentability of genetic information applied to diagnostics and therapeutics of cancer is also discussed.
Зміст
Central Nervous System Tumors.- Head and Neck Tumors.- Thyroid Cancer.- Targeted Therapies for Non-Small Cell Lung Cancer.- Non-Hodgkin Lymphomas.- Leukemias.- Breast Cancer.- Esophago-Gastric Cancer.- Colorectal Cancer.- Hepatocellular Carcinoma.- Biomarkers for Prognosis and Molecularly Targeted Therapy in Renal Cell Carcinoma.- Bladder Cancer.- Biomarkers in Prostate cancer.- Ovarian Cancer.- Uterine Cancer: The Influence of Genetics and Environment on Cell Cycling Pathways in Cancer.- Biotargets in Sarcomas: The Past, Present and a Look into the Future.- Melanoma and other skin cancers.- Molecular pathology of cancer metastasis: suggestions for future therapy.- Current and future developments in cancer therapy research: mi RNAs as new promising targets or tools.
Про автора
Mauro Bologna, MD
University of L’Aquila, L’Aquila, Italy
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