Epigenetics and Health
An incisive and contemporary discussion of epigenetic phenomena applied to human health and disease
Epigenetics and Health: A Practical Guide delivers a thorough and insightful exploration of the basic principles of gene function, gene regulation, and gene expression. The author explains how epigenetic modifications alter gene expression and demonstrate the role played by environmental factors–including nutrition, exercise, toxins, and stress–in gene regulation, as well as their potential health consequences.
The book presents current methods for analyzing epigenetic variation, including NGS applications and bioinformatic analysis.
Readers will be encouraged to question, analyze, and critically appraise the literature on epigenetics to further develop their understanding. They’ll also find:
* Explorations of epigenetic mechanisms, homeostasis, and the potential for manipulating the epigenome
* Practical discussions of methods for epigenetic analyses
* How to address cancer epigenetics, mental health epigenetics, and guidance on developing an epigenetics research project
Epigenetics and Health: A Practical Guide will benefit practicing geneticists and medical geneticists seeking insights into epigenetic phenomena applied to human health and disease.
Зміст
Preface
Chapter 1: How do genes work?
Chapter 2: What is Epigenetics?
Chapter 3: Epigenetic mechanisms, homeostasis and potential for manipulating the epigenome
Chapter 4: Methods for epigenetic analyses
Chapter 5: Aging and epigenetic variation
Chapter 6: Cancer Epigenetics
Chapter 7: Epigenetics and Mental health
Chapter 8: Implications of epigenetic research and Getting Started
Про автора
Michelle Mc Culley, Ph D, is an Associate Professor in the Department of Pathology and Molecular Medicine at the University of Otago in New Zealand. Her research is focused on the epigenetic regulation of our genes, particularly as it relates to environment, health, and disease.
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