R. VERPOORTE Division of Pharmacognosy, section Metabolomics, IBL, Leiden University PO Box 9502, 2300RA Leiden, The Netherlands, Email: [email protected] Univ.NL In the past years the interest in plant secondary has increased rapidly. Three major reasons can be mentioned for this. First because plants are a major source for the production of medicines and the development of novel medicines; second because plants contain health promoting secondary metabolites, third because of the interest in the resistance of plants against pests and diseases in which the secondary metabolism plays a crucial role. Seven years ago we edited a book (Verpoorte and Alfermann 2000) on the engineering of plant secondary metabolism. A general overview was given of plant secondary metabolism, and the strategies one could envisage for engineering plant secondary metabolite pathways. Furthermore, a number of examples were presented describing the state-of-the-art of engineering plant secondary metabolism. Now we have again compiled a series of papers on the engineering of plant metabolism.
Зміст
Biosynthesis of Plant Natural Products and Characterization of Plant Biosynthetic Pathways in Recombinant Microorganisms.- Plant Molecular Farming: Host Systems, Technology and Products.- Plastid Pathways.- Metabolic Engineering of the Alkaloid Biosynthesis in Plants: Functional Genomics Approaches.- Polyamine Biosynthetic Pathway: A Potential Target for Enhancing Alkaloid Production.- Metabolic Engineering in Alkaloid Biosynthesis: Case Studies in Tyrosine- and Putrescine-Derived Alkaloids.- Application of Metabolic Engineering to Vanillin Biosynthetic Pathways in Vanilla Planifolia.- Pathway Engineering of the Plant Vitamin C Metabolic Network.- Metabolic Engineering of Terpenoid Biosynthesis in Plants.- Metabolic Engineering of Seed Oil Biosynthetic Pathways for Human Health.- Metabolic Engineering in Sugarcane: Assisting the Transition to a Bio-based Economy.- Single-chain Fv Antibody Stimulates Biosynthesis of Secondary Metabolites in Plants.- Metabolic Engineering of Sulfur Assimilation in Plants.- Approaches to Quality Plant Based Medicine: Significance of Chemical Profiling.
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