What are the functions of mitochondria in the human body? Why might they stop working properly and what can happen as a result? How can personalized nutrition help to optimize mitochondrial function and prevent or address chronic conditions?
This innovative book explores the incredibly complex biochemical roles of mitochondria in health and disease. When healthy, mitochondria provide us with ninety percent of our body’s energy. When unhealthy, this can lead to many chronic and degenerative conditions including cancer and Alzheimer’s disease. This guide helps practitioners to identify the mitochondrial dysfunction underlying a wide range of health complaints, and provides inspiration about relevant and emerging mitochondria-supportive dietary regimes and nutrients to explore within the model of personalized nutrition.
Зміст
Foreword – Lorraine Nicolle. Part One – Mitochondria: The doorway to understanding the body as a whole. 1. What are mitochondria? 2. Evolution and mitochondria. 3. Energy production. 4. Mitochondrial dynamics: Shape-shifting mitochondria on the move. 5. Mitochondria: The original multi-fuel burners and the need for metabolic flexibility. 6. Acetyl-Co A: Much more than an energy source. 7. Catabolic and anabolic: How mitochondria initiate the change from burning fuel to cell building. 8. Ketone metabolism. 9. Mitochondria and the immune system. 10. Creatine: The mitochondrial ATP assistant. 11. Calcium and mitochondria: Conductors of the cell ‘orchestra’. 12. Apoptosis: (Programmed cell death). 13. Iron and mitochondria: A matter of life and death. 14. Urea: Liver mitochondria help to clear ammonia. 15. Health, toxicity and hormesis. Part Two – The influence of mitochondria in disease. 16. Insulin resistance and type 2 diabetes. 17. Hypertension. 18. The heart. 19. Cholesterol metabolism. 20. Autoimmunity and mitochondria: The emerging field of immunometabolism. 21. Fatigue. 22. Neurodegeneration. 23. Cancer. 24. Osteoarthritis. 25. Osteoporosis. 26. Chronic Pain. 27. Depression. 28. Autism Spectrum Disorders.
Про автора
Lorraine Nicolle MSc is a nutrition practitioner with a regular clinic at a London-based natural health centre. Lorraine is also a nutrition lecturer and module leader on university-validated degree and post-graduate courses. She works with a healthcare company, writing and delivering nutrition education sessions for healthcare practitioners, and runs workplace nutrition programmes for businesses. She is a recent recipient of the CAM Award. For more information, see www.lorrainenicollenutrition.co.uk.
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