This book constitutes the thoroughly refereed post-conference proceedings of the 15th Nordic Conference in Secure IT Systems, Nord Sec 2010, held at Aalto University in Espoo, Finland in October 2010. The 13 full papers and 3 short papers presented were carefully reviewed and selected from 37 submissions. The volume also contains 1 full-paper length invited talk and 3 revised selected papers initially presented at the OWASP App Sec Research 2010 conference. The contributions cover the following topics: network security; monitoring and reputation; privacy; policy enforcement; cryptography and protocols.