Cancer research is now an interdisciplinary effort requiring a basic knowledge of commonly used terms, facts, issues, and concepts. This interdisciplinary book meets this need, providing an authoritative overview to the field. It presents many of the molecules and mechanisms generally important in human cancers and examines a broad, but exemplary, selection of cancers. In addition, cancer research has now reached a critical stage, in which the accumulated knowledge on molecular mechanisms is gradually translated into improved prevention, diagnosis, and treatment. This book summarizes the state, pitfalls, and potential of these efforts.
Зміст
Part I.
1 An Introduction to Human Cancers.
2 Tumor Genetics.
3 DNA Damage and DNA Repair.
4 Oncogenes.
5 Tumor Suppressor Genes.
6 Cancer Pathways.
7 Apoptosis and Replicative Senescence in Cancer.
8 Cancer Epigenetics.
9 Invasion and metastasis.
Part II.
10 Leukemias and Lymphomas.
11 Wilms Tumor (nephroblastoma).
12 Cancers of the skin.
13 Colon Cancer.
14 Bladder Cancer.
15 Renal Cell Carcinoma.
16 Liver Cancer.
17 Stomach Cancer.
18 Breast Cancer.
19 Prostate Cancer. Part III.
20 Cancer Prevention.
22 Cancer Therapy.
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