The book provides an in-depth and comprehensive overview of the essential role of non-coding RNAs (nc RNAs) in bone formation. In combination with researches from multiple scholars in this field, the book reviews the mechanisms of nc RNA-related bone diseases, as well as the potential applications of RNA synthesis technology in bone disorder treatments. This volume covers the following topics: 1) basic introduction of non-coding RNA and bone development, how 2) micro RNAs and 3) long noncoding RNAs (Lnc RNAs) regulate bone formation, 4) how nc RNAs and the corresponding pathways participate in bone metabolism diseases, 5) RNA synthesis technology and the possible RNA therapies in bone disease. Researchers and students in the fields of human genetics, human physiology, developmental biology and biomedical engineering, as well as professionals and scientists in Orthopedics, will particularly find this book helpful.
Mục lục
Preface.- Part I Micro RNAs and Bone.- Chapter 1 Micro RNAs and Osteoporosis.- Chapter 2 Micro RNAs and the Diagnosis of Osteoporosis.- Chapter 3 Micro RNAs and Osteoarthritis.- Chapter 4 Mechanosensitive mi RNAs and Bone Formation.- Part II Long non-coding RNAs and Bone.- Chapter 5 Roles and Mechanism of Long Noncoding RNAs in Bone Diseases.- Chapter 6 Lnc RNAs that Regulate Oosteoblast Function and Bone Formation.- Part III RNA Synthesis Technology and RNA Therapy in Bone Diseases.- Chapter 7 Synthetic Technology of Non-coding RNAs Used in Bone Disease Research and Therapeutics.- Chapter 8 RNA Therapy in Bone Diseases.
Giới thiệu về tác giả
Dr. Airong QIAN is a professor at School of Life Sciences, Northwestern Polytechnical University, Xi’an, China. She serves as the director of “NPU-UAB” International Joint Laboratory of Bone Metabolism at this University.
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