This volume provides the most updated knowledge on the advancement of molecular pathogenesis, molecular diagnosis, and therapy development for hepatocellular carcinoma (HCC). Topics covered include the etiology and pathogenesis of HCC, recent advances in HCC genomics, biomarker discovery and validation in HCC diagnosis, the role of liver biopsy in HCC early diagnosis, and the future prospects of surgical approaches and targeted therapy for HCC. In addition to reviewing the current available knowledge, the book also discusses the future development of a precision and personalized medicine approach for HCC.
Written by experts in the field, Precision Molecular Pathology of Liver Cancer is a concise yet comprehensive resource for practitioners who treat patients with hepatocellular carcinoma.
€96.29
Mục lục
Overview: Current diagnosis and treatment of HCC in the era of precision medicine.- The etiology and pathogenesis of hepatocellular carcinoma.- Histological classification of HCC and its clinical implication.- Molecular classification of HCC and precision medicine.- Recent advances in HCC genomics, next generation sequencing, and bioinformatics.- Epigenetic regulations in the pathogenesis of HCC and the clinical application.- Biomarker discovery and validation in HCC diagnosis, prognosis, and therapy.- HCC cancer stem cell signaling pathway.- Epithelial and mesenchymal transition (EMT) and its biological significance in HCC.- HCC metastasis and circulating tumor cells.- Biological role and potential clinical application of mi RNA in hepatocellular carcinoma.- Immune regulation in HCC and the prospect of immunotherapy.- Liver cell dysplasia and the development of HCC.- Molecular pathogenesis of hepatic adenoma and its malignant transformation.- The role of liver biopsy in HCC early diagnosis and treatment decision.- The future prospect on surgical approaches for HCC.- The future prospect on targeted therapy for HCC.Giới thiệu về tác giả
Chen Liu, MDUniversity of Florida
FL, USA
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Ngôn ngữ Anh ● định dạng PDF ● Trang 271 ● ISBN 9783319680828 ● Kích thước tập tin 8.3 MB ● Biên tập viên Chen Liu ● Nhà xuất bản Springer International Publishing ● Thành phố Cham ● Quốc gia CH ● Được phát hành 2018 ● Có thể tải xuống 24 tháng ● Tiền tệ EUR ● TÔI 5582614 ● Sao chép bảo vệ DRM xã hội
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