David B. (University of Pennsylvania, Philadelphia, USA) Weiner & William V. (University of Pennsylvania School of Medicine, Philadelphia, ) Williams 
Biological Approaches to Rational Drug Design [PDF ebook] 

This book exploits an understanding of disease pathogenesis by applying a variety of biological agents to therapy. It provides a broad overview of the current methodologies being applied to biological approaches to rational drug design and in depth analyses of progress in this specific field.