Like its predecessor, Organic Synthesis Highlights II surveys recent accomplishments and current trends in synthetic organic chemistry.
Part I describes new methods and reagents including asymmetric carbon-carbon bond formation with metallocenes and with enzymes, via temporary silicon connections, and by means of carbohydrate complexes. Part II describes landmarks in the synthesis of natural products and surveys synthetic strategies to different classes of natural products.
The forty essays in this volume bear witness to the creativity and talent which have led to the recent advances in the field. Both advanced students and researchers active in the field will welcome this as a source of ideas and inspiration.
Mục lục
New Methods and Reagents for Organic Synthesis
Enantioselective Deprotonation and Protonation/
Carbohydrate Complexes in Enantioselective Carbon-Carbon Bond Formation
Asymmetric Aza-Diels-Alder Reactions
Iron eta5-Complexes in Organic Synthesis
Rhodium-Catalyzed Carbenoid Cyclizations
Enzymatic Synthesis of O-Glycosides
Electrophilic Cyclizations in the Synthesis of Heterocycles
Polycyclization as a Strategy in the Synthesis of Complex Alkaloids
Domino Reactions
Group Selective Reactions
Hypervalent Iodine Reagents
Taxanes: An Unusual Class of Natural Products
CC-1065: One of the Most Powerful Anti-Tumor Compounds
Synthesis of Calicheamicin
Total Synthesis of Rapamycin
Giới thiệu về tác giả
Herbert Waldmann (b 1957) received his Ph D in 1985 from the University of Mainz (Germany) with H. Kunz. After postdoctoral studies (1985-1986, Harvard University, George Whitesides) and habilitation (1991, University of Mainz) he was appointed associate professor at the University of Bonn in 1991. In 1993 he moved to the University of Karlsruhe as Full Professor of Organic Chemistry. In 1999 he was appointed Director at the Max Planck Institute of Molecular Physiology in Dortmund, where he is heading the Department of Chemical Biology. He also holds a Professorship in Biochemistry at the University of Dortmund. Herbert Waldmann has been the recipient of the Friedrich Weygand Award for the advancement of peptide chemistry, of the Carl Duisberg Award of the Gesellschaft Deutscher Chemiker, the Otto-Bayer-Award and the Steinhofer Award of the Steinhofer Foundation.His current research interests include bioorganic chemistry and natural product synthesis as well as biocatalysis, stereoselective synthesis and combinatorial chemistry.
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