The book will benefit a reader with a background in physical sciences and applied mathematics interested in the mathematical models of genetic evolution. In the first chapter, we analyze several thought experiments based on a basic model of stochastic evolution of a single genomic site in the presence of the factors of random mutation, directional natural selection, and random genetic drift. In the second chapter, we present a more advanced theory for a large number of linked loci. In the third chapter, we include the effect of genetic recombination into account and find out the advantage of sexual reproduction for adaptation. These models are useful for the evolution of a broad range of asexual and sexual populations, including virus evolution in a host and a host population.
Igor M. Rouzine
One-Locus and Multi-Locus Theory and Recombination [PDF ebook]
One-Locus and Multi-Locus Theory and Recombination [PDF ebook]
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Ngôn ngữ Anh ● định dạng PDF ● Trang 181 ● ISBN 9783110615456 ● Nhà xuất bản De Gruyter ● Được phát hành 2020 ● Có thể tải xuống 3 lần ● Tiền tệ EUR ● TÔI 9434099 ● Sao chép bảo vệ Adobe DRM
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