It has become increasingly clear that psoriatic disease, both of the skin and joints, can be a significant diagnostic and therapeutic challenge for the physician and a debilitating illness for the patient. Genetic and immunologic advances have increased our understanding of the pathophysiology of psoriasis and psoriatic arthritis and there is a need for practically oriented evidence based references to describe the management options open to clinicians. The speed at which developments are occurring in the field also necessitates a novel approach to keeping up with these changes in practice and the need is for a reference that that be updated regularly as the subject requires. Psoriasis is an incredibly fast-moving discipline within dermatology. Guidelines, treatment options and management all change at incredible speed. There is a requirement to provide a comprehensive reference resource to provide practical, user friendly information for the dermatology profession to aid in the decision-making process. Psoriasis is a graphical subdiscipline of medicine and therefore this will have copious illustrations. As a fast moving discipline the emphasis must be on annual updates to ensure that readers are kept up to date on the important areas of development.
Mục lục
Introduction to Psoriasis and Psoriasis Therapy.- Pathophysiology of Psoriasis/Novel Pathways.- Psoriasis and Psoriasis Arthritis: Clinical Review and Update.- Overview of Therapeutic Options/Pharmacology.- Topical Therapy.- Ultraviolet and Laser Therapy.- Traditional Systemic Therapy.- Biologics I: TNF Inhibitors.- Biologics II: IL-12/23 and T-Cell Targeted Therapy.- Research Pipeline I: Topicals and Oral Therapies.- Research Pipeline II: Biologic Therapies.- Summary of Published Treatment Guidelines.- Reimbursement Issues/Aides.- Patient Support Programs and Organizations.- Conclusion.- Appendix: Directory of Helpful Websites/Online Resources/Telephone Numbers.
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