Learn about the analytical tools used to characterize particulate drug delivery systems with this comprehensive overview
Edited by a leading expert in the field, Characterization of Pharmaceutical Nano- and Microsystems provides a complete description of the analytical techniques used to characterize particulate drug systems on the micro- and nanoscale.
The book offers readers a full understanding of the basic physicochemical characteristics, material properties and differences between micro- and nanosystems. It explains how and why greater experience and more reliable measurement techniques are required as particle size shrinks, and the measured phenomena grow weaker.
Characterization of Pharmaceutical Nano- and Microsystems deals with a wide variety of topics relevant to chemical and solid-state analysis of drug delivery systems, including drug release, permeation, cell interaction, and safety. It is a complete resource for those interested in the development and manufacture of new medicines, the drug development process, and the translation of those drugs into life-enriching and lifesaving medicines.
Characterization of Pharmaceutical Nano- and Microsystems covers all of the following topics:
* An introduction to the analytical tools applied to determine particle size, morphology, and shape
* Common chemical approaches to drug system characterization
* A description of solid-state characterization of drug systems
* Drug release and permeation studies
* Toxicity and safety issues
* The interaction of drug particles with cells
Perfect for pharmaceutical chemists and engineers, as well as all other industry professionals and researchers who deal with drug delivery systems on a regular basis, Characterization of Pharmaceutical Nano- and Microsystems also belongs on bookshelves of interested students and faculty who interact with this topic.
Mục lục
1. Selecting a Particle Sizer for the Pharmaceutical Industry
Professor Maria Margarida Figuiredo ([email protected])
2. Spectroscopic methods in solid-state characterization
Professor Clare Strachan ([email protected])
3. Microfluidic analysis techniques for safety assessment of pharmaceutical nano- and microsystems
Dr Tiina Sikanen([email protected])
4. In Vitro In Vivo Correlation for Pharmaceutical Nano and Microsystems
Prof. Vandana Patravale ([email protected])
5. Characterization of Bioadhesion, Mucin-interactions and Mucosal Permeability of Pharmaceutical Nano- and Microsystems
Ellen Hagesaether, Marianne Hiorth and Prof Ingunn Tho ([email protected])
6. Cell-Nanoparticle Interactions: Toxicity and Safety Issues
Helder Santos ([email protected])
7. Intestinal mucosal tissue models to validate functionalized nanosystems
Bruno Sarmento ([email protected])
8. Biodistribution of polymeric, polysaccharide and metallic nanoparticles
Erem Bilensoy ([email protected])
9. Opportunities and challenges of silicon-based nanoparticles for drug delivery and imaging
Jessica Rosenholm ([email protected])
10. Statistical Analysis and Multidimensional Modelling in Research Osmo Antikainen ([email protected])
Giới thiệu về tác giả
Leena Peltonen is Adjunct Professor in the Division of Pharmaceutical Chemistry and Technology at the University of Helsinki, Finland. She holds two master’s degrees, as well as a Ph D in Pharmacy that she obtained in 2001.
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