To celebrate the Center for Perinatal Biology’s 40th Anniversary, an illustrious group gathered at Loma Linda University in February 2013. That gathering of experts and this volume of the proceedings are a tribute to the founder of the Center, Lawrence D. Longo, M.D. These chapters present contributions from individuals who in some way or another were influenced by Dr. Longo. Covering a wide range of topics, and illustrating the diversity of thinking and scientific interests, these proceedings address basic science through to clinical problems in the developmental programming of health and disease.
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“Surprised by Joy” – Four Decades of Contributions to Developmental Physiology.- s GC-c GMP Signaling: Target for Anticancer Therapy.- Lawrence D. Longo. From Chronic Fetal Hypoxia to Proteomic Predictors of Fetal Distress Syndrome: A life devoted to research and mentoring based on virtue-ethics.- Pregnancy Programming and Preeclampsia: Identifying a Human Endothelial Model to Study Pregnancy-Adapted Endothelial Function and Endothelial Adaptive Failure in Preeclamptic Subjects.- Regulation of Amniotic Fluid Volume: Evolving Concepts.- Gestational Diabetes, Preeclampsia and Cytokine Release: Similarities and Differences in Endothelial Cell Function.- Heart Disease Link to Fetal Hypoxia and Oxidative Stress.- Fetal Breathing Movements and Changes at Birth.- From Fetal Physiology to Gene Therapy – It All Started in Loma Linda.- 30+ Years of Exercise in Pregnancy.- Gap Junction Regulation of Vascular Tone: Implications of Modulatory Intercellular Communication during Gestation.- Effect of Preeclampsia on Placental Function: Influence of Sexual Dimorphism, micro RNA’s and Mitochondria.- Altitude, Attitude and Adaptation.- The Separation of Sexual Activity and Reproduction in Human Social Evolution.- The Influence of Growth Hormone on Bone and Adipose Programming.- The Fetal Cerebral Circulation: Three Decades of Exploration by the LLU Center for Perinatal Biology.- Placental Vascular Defects in Compromised Pregnancies: Effects of Assisted Reproductive Technologies and Other Maternal Stressors.- How to Build a Healthy Heart from Scratch.- Estrogen in the Fetus.- Calcitonin Gene Related Family Peptides: Importance in Normal Placental and Fetal Development.
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