The original intent of the series Studies of Brain Function was to offer a forum to neurobiologists working in different fields to present some of their recent results in a more extensive way. What may have been or might be published in several papers appearing in different journals will thus be com- bined in one monograph, thus making the data more easily available to a wider scientific community. It is also believed that such an attempt will provide a more comprehensive insight into one particular field of neurobiol- ogy. Admittedly, the monograph will represent a more subjective view than that provided by a classical review article. In this monograph I am going to describe a major aspect of my research, i.e., the central processing of information arising from the receptors in the semicircular canals and otoliths of the inner ear. I shall restrict this report to those systems that are concerned with the vestibuloocular transmission, since they offer particular opportunity to study sensory-motor integration.