‘Preimplantation Genetic Diagnosis’ (PGD) offers an answer in the control of inherited conditions by predicting reproductive outcome. PGD is no longer an experimental procedure, having become an integral part of genetic practices and assisted reproduction technology. Therefore this practical book will be vital for clinicians to access a comprehensive description of available experience, indications, methods, and clinical outcomes.
The book describes the experience of PGD, demonstrating the considerable progress made in this revolutionary procedure and describing its utility within different patient groups, the accuracy of the laboratory methods, and prediction of the reproductive outcome. This will facilitate the use of PGD by practicing physicians, who may be able to offer patients this novel option for avoiding the birth of an affected child and having healthy children of their own.
Mục lục
Primary Prevention of Genetic Disorders and Place of Preimplantation Genetic Diagnosis.- Approaches to Preimplantation Genetic Diagnosis.- Preimplantation Genetic Diagnosis for Single Gene Disorders.- Preimplantation HLA Typing.- Preimplantation Genetic Diagnosis for Chromosomal Disorders.- Clinical Outcomes Following Preimplantation Genetic Diagnosis.- Preimplantation Genetic Diagnosis and Establishment of Human Embryonic Stem Cell Lines.- Ethical, Social, and Legal Issues.
Giới thiệu về tác giả
Yury Verlinksy and Anver Kuliev are two of the most respected names in the practice of perimplantation genetic diagnosis. Both work at the Reproductive Genetics Institute in Chicago, IL, USA, which is one of the most advanced and well-regarded medical institutions in the world in providing high quality services for infertility problems and genetic disorders.
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