Regulating virtually all biological processes, the genome’s 2, 654 newly discovered variants of mature micro RNAs – short ribonucleic acid molecules found in eukaryotic cells – hold a key role in the body’s toolkit of regenerative and reparative capacities. Identifying how to activate and deliver these specialist molecules may aid in the repair and regeneration of major tissue and organ damage in future therapies. In Micro RNA and Regenerative Medicine, Second Edition, over 50 leading experts address foundational and emerging topics in the field. Concisely summarizing and evaluating key findings from new research and their translational application, contributors examine current and future significance of clinical research in the mi RNA area. Coverage encompasses all major aspects of fundamental stem cell and developmental biology, including the uses of mi RNA in cell and tissue plasticity, developmental biology, tissue repair, and regeneration. In particular, contributors provide focused coverage of methodologies for regenerative intervention and tissue engineering. Topics new to this edition include proteomic changes during tissue repair and regeneration, horizontal transfer of mi RNAs in tissue regeneration, tissue stemness, peripheral nerve regeneration, mi RNA as biomarkers, micro RNA in pregnancy and embryo development, exogenous and diet derived micro RNA in tissue development, ocular micro RNA, mitochondrial micro RNA, sensory hair cell death and regeneration, and micro RNA in senescence. – Features chapter contributions from international leaders in the field, covering the spectrum from bench to bedside- Includes short, applied chapters offering focused discussion and practical examples- Incorporates multi-color text layout with more than 150 color figures to illustrate important findings
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