Caldesmon is one of the most abundant proteins detected in smooth muscle and in a number of non-muscle cells. It binds actin, myosin, tropomyosin and calmodulin and is believed to play in smooth muscle a regulatory role similar to that of troponin in striated muscle. Two closely-related isoforms of caldesmon being the products of an alternative splicing of a single gene, have been identified. The high molecular weight (H-Ca D) isoform is expressed predominantly in smooth muscle, whereas the low molecular weight (L-Ca D) isoform is found in non-muscle tissues and cells. This book examines the anatomy and physiology of caldesmon proteins.
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格式 PDF ● 网页 135 ● ISBN 9781628086683 ● 编辑 Edward A Czurylo & Natalia Kulikova ● 出版者 Nova Science Publishers ● 发布时间 2013 ● 下载 3 时 ● 货币 EUR ● ID 7223462 ● 复制保护 Adobe DRM
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