Presented here are recent advances in biochemical, toxicological, and regulatory aspects of oxidative drug metabolizing enzymes. Mainly cytochrome P450-dependent and flavin-containing monooxygenases (FMO) are covered. Moreover, the book deals with genotoxicity studies and toxicological interactions of environmental chemicals and mechanisms of mutagenicity and tumor formation. The construction of genetically engineered mammalian cells for the production of a specific P450 isozyme and the application of these cell lines in drug metabolism, mutagenicity and toxicity studies are described in detail. Further, insight is provided into how a number of aquatic species cope with pollutants and their genotoxicity.
€114.69
购买此电子书可免费获赠一本！
语言 英语 ● 格式 PDF ● ISBN 9783642795282 ● 编辑 Emel Arinc & Ernest Hodgson ● 出版者 Springer Berlin Heidelberg ● 发布时间 2013 ● 下载 3 时 ● 货币 EUR ● ID 6333510 ● 复制保护 Adobe DRM
需要具备DRM功能的电子书阅读器
来自同一作者的更多电子书 / 编辑
17,524 此类电子书
