Jun Chen & John H. Zhang 
Non-Neuronal Mechanisms of Brain Damage and Repair After Stroke [PDF ebook] 

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This book provides a comprehensive overview of the latest research in the role of non-neuronal cells – astrocytes, oligodendrocytes, endothelial cells, pericytes, microglia, and other immune cells in ischemic brain injury and long-term recovery. In these cases, neurodegeneration and brain repair are controlled in a sophisticated system, incorporating interactions between different cell types and cellular systems. Also explored are the therapeutic strategies that target non-neuronal responses after stroke and their translational potentials.

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Part 1. Microvascular integrity in stroke.- 1. Structural alterations to the endothelial tight junction complex during stroke.- 2. Role of pericytes in neurovascular unite and stroke.- 3. Glial support of blood-brain barrier integrity: Molecular targets for novel therapeutic strategies in stroke.- 4. Barrier mechanism in neonatal stroke.- 5. Angiogenesis: a realistic therapy for ischemic stroke.- Part 2. Glial cells in stroke.- 6. Astrocytes as a target for ischemic stroke.- 7. Microglia: a double-sided sword in stroke.- 8. Crosstalk between cerebral endothelium and oligodendrocyte after stroke.- Part 3. Peripheral immune cells in stroke.- 9. The peripheral immune response to stroke.- 10. The Role of spleen-derived immune cells in ischemic brain injury.- 11. Regulatory T cells in ischemic brain injury.- 12. B cells in stroke and preconditioning-induced protection against stroke.- 13. Mast cell as an early responder in ischemic brain injury.- 14. Roles of neutrophils in stroke.- 15. Thefunction of cytokines in ischemic stroke.- Part 4. White matter injury and repair in stroke.- 16. Ischemic injury to white matter: an age-dependent process.- 17. Neurovascular repair after stroke.- 18. The role of non-neuronal Nrf2 pathway in ischemic stroke: damage control and potential tissue repair.- 19. Stem cell therapy for ischemic stroke.

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语言 英语 ● 格式 PDF ● 网页 408 ● ISBN 9783319323374 ● 文件大小 14.0 MB ● 编辑 Jun Chen & John H. Zhang ● 出版者 Springer International Publishing ● 市 Cham ● 国家 CH ● 发布时间 2016 ● 下载 24 个月 ● 货币 EUR ● ID 4955164 ● 复制保护 社会DRM

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