Klara Valko 
Physicochemical and Biomimetic Properties in Drug Discovery [PDF ebook] 
Chromatographic Techniques for Lead Optimization

Demonstrating how and why to measure physicochemical and biomimetic properties in early stages of drug discovery for lead optimization, Physicochemical and Biomimetic Properties in Drug Discovery encourages readers to discover relationships between various measurements and develop a sense of interdisciplinary thinking that will add to new research in drug discovery. This practical guide includes detailed descriptions of state-of-the-art chromatographic techniques and uses real-life examples and models to help medicinal chemists and scientists and advanced graduate students apply measurement data for optimal drug discovery.

关于作者

KLARA VALKO is an Investigator in the Analytical
Chemistry Department of Molecular Discovery Research at
Glaxo Smith Kline. Dr. Valko has more than thirty years of experience
in HPLC, GC, and LC/MS. She also has more than ten years of
experience teaching physicochemical measurements and ADME
optimization tools at the UCL School of Pharmacy. Currently, Dr.
Valko is an Honorary Professor, leading the Physchem/ADME module
for a drug discovery MSc course.