Viruses interact with all forms of life and have shaped evolution for 4
billion years. The COVID-19 pandemic highlights the importance of
conducting scientific research into viruses to understand the interactions
between them and their hosts.
Virology is made up of eight chapters, all of which have been written by
outstanding female virologists, emphasizing women s fundamental role
in all aspects of science. It summarizes our current knowledge about the
biology of viruses in general and analyzes the specific features of several
ones of medical, veterinary and agricultural importance. Genome
replication strategies of different virus families are covered, as well as
strategies for survival within their hosts by counteraction of the cellular
innate antiviral responses. Attention is also given to viral strategies for
efficient dissemination in nature, as well as the evolution of a select
group of viruses.
关于作者
Maria Carla Saleh is Full Professor at Institut Pasteur, where she directs
the Viruses and RNAi unit within the department of Virology. She studies
the antiviral response in insects and develops new vector control
strategies to eliminate mosquito-borne diseases. During her postdoctoral training at the University of California, San Francisco, USA, she
discovered that RNA interference was the antiviral immune system of
insects.
Felix Augusto Rey directs the Structural Virology unit of Institut Pasteur,
France, where he studies the entry mechanisms of lipid-enveloped
viruses into cells by using structural approaches. Previously, he has
been junior group leader at the CNRS and was chair of Institut Pasteur?s
Virology department between 2004 and 2012. During his post-doctoral
training at Harvard University, USA, he determined the first structure of
a flavivirus envelope protein.
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