In this book, the authors discuss the genetics, geographic variation and disorders associated with skin pigmentation. Topics include the melanocortin-1 receptor as a key melanoma risk determinant and a critical regulator of the UV DNA damage repair response; three major signaling pathways involved in the establishment of mammalian skin and hair coloration via the regulation of tyrosinase activity; multiple genes and diverse hierarchical pathways that affect human pigmentation; acquired skin pigmenation; the pro-opiomelanocortin (POMC) and melanocortin systems in the regulation of human skin pigmentation; and an overview on the melanocyte precursor migration from neural cres.
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格式 PDF ● 网页 221 ● ISBN 9781626184183 ● 编辑 Mary B. Haworth & John B Smith ● 出版者 Nova Science Publishers ● 发布时间 2013 ● 下载 3 时 ● 货币 EUR ● ID 7222852 ● 复制保护 Adobe DRM
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