作者: Platts-Mills

Just as the magnitude of the growth and developmental problems attributable to human helminthiasis are being fully realized, we are able for the first time to describe defined immune responses giving …

B cells used to be considered as a homogeneous population of cells destined to produce antibodies of increasing affinity and to maintain an immunological memory. In recent years, it has been determin …

The explosion of information on immuneneuroendocrine interactions has continued unabated since the first and second editions of this volume appeared in 1988 and 1992. This third revised and enlarged …

The contributions collected in this volume represent the most recent findings, reviewed by leading scientists in the field, on several different aspects of IL-12 biology. The opening chapter analyzes …

Intracellular prokaryotic and eukaryotic organisms cause some of the most intractable problems in the fields of human and animal infectious diseases. Such infections are characteristically long and c …

There are more T cells in the gastrointestinal tract and lung than in the rest of the body combined. The aim of this book is to cover all the important aspects of the biology of these cells in animal …

Chemokines are a superfamily of small proteins which play a crucial role in immune and inflammatory reactions and in viral infection. They attract and activate leukocytes and regulate diverse cellula …

In a world full of pathogens the ability to detect an incipient infection and to respond rapidly and appropriately to it is a decisive part of our survival strategy. The innate immune system provides …

In recent years, CD38 has emerged from a simple differentiation marker to a multifunctional cell surface protein. It can serve as an ectoenzyme that catalyzes the synthesis and hydrolysis of a Ca2+mo …

Eosinophils represent approximately 1% of peripheral blood leukocytes and play a central proinflammatory and immunoregulatory role in various immune disorders. This volume provides the reader with a …

Catalytic antibodies have attracted attention because they can combine exquisite specificity with permanent and potent antigen inactivation. The field has enjoyed a renaissance in recent years due to …

This book explores the celllular and molecular mechanisms involved in asthma and allergic diseases, from basic immunology to the treatment of patients. Arising from a special symposium held to celebr …

Over the last 15 years, since the discovery of the T cell receptor gamma and delta genes, rapid progress has been made toward the understanding of the biology of gamma-delta T cells. They differ from …

Despite extensive efforts to control it, malaria is still one of the most devastating infectious diseases worldwide. This book, now in its second edition, provides a broad and up-to-date overview of …

The importance of fungal organisms as allergens and pathogens has been increasing considerably over the last decade. This is due, on the one hand, to a general increase in the incidence of allergies, …

The incidence of allergies is increasing worldwide. Beside the well-established symptomatic treatments and subcutaneous immunotherapies, formerly known as de- or hyposensitization, a new form of trea …

In the past, neutrophils were often reduced to their ability to release preformed mediators and kill pathogens. The present volume of Chemical Immunology and Allergy, however, offers a very broad and …

In the western world, the prevalence of allergy and asthma has increased two- to threefold over the last 40 years and has reached epidemic proportions. This book represents the first complete documen …

Epithelial defense against infectious agents relies on the recognition of microbial products by pattern recognition receptors and the local production of antimicrobial peptides. This book provides a …

Basophils and mast cells are similar but unique secretory cells which play a central role in inflammatory and immediate allergic reactions. In this book, the author reviews the ultrastructural studie …

The discovery of Ig E and its association with mast cell histamine release provided the initial understanding of the role of mast cells in asthma and acute allergic reactions. However, mast cells are …

Infertility is an increasing problem in many societies. The success rate of assisted reproduction is still below 30%, although the treatments and techniques have improved continuously. An important b …

Pregnancy is a unique symbiotic union between mother and fetus which contradicts many of the general rules of immunology. The maternal immune system reacts towards the foreign tissue, but instead of …

The inverse correlation between allergic diseases and helminth infections has been debated for over 30 years. It was initially assumed that the underlying mechanism is an imbalance between Th1 and Th …

Allergic diseases and asthma constitute a growing health care problem with a marked socioeconomic impact, especially in industrialized countries. This book summarizes what is currently known about th …

The second edition of Immune ‘Response and the Eye’ highlights recent insights into the ‘dangerous compromise’ between the immune system and the eye, which protects the eye against pathogens while li …

Superantigens constitute a growing family of bacterial and viral proteins that share the capacity of inducing massive activation of the immune system. This volume contains contributions from leaders …

The prevalence of allergic diseases has increased dramatically over recent decades, both in terms of the number of sufferers and the number of allergies. This is a trend that has frequently been refe …

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Angiogenesis, the formation of new blood vessels, is fundamental for physiological processes such as embryonic and postnatal development, wound repair, and reproductive functions. Angiogenesis plays …

This book presents the state of the art in cellular and molecular mechanisms regulating the immune response in allergic inflammation. Special attention is given to the central role of regulatory T ce …

Anaphylaxis is the most dramatic and potentially life-threatening manifestation of an immediate-type hypersensitivity reaction. Although known for over 100 years, it still poses many unresolved quest …

Allergy and allergic diseases have increased in prevalence worldwide during the last decade. Relevant determinants influencing the development of allergic inflammation come from the environment and a …

The skin is one of the most frequently involved organs in adverse drug reactions. Occurring with an incidence of 1-5% for certain types of drugs, cutaneous drug eruptions are mostly benign in nature, …

In recent decades, it has become increasingly clear that the immune and nervous systems communicate with each other in a bidirectional way. The role of chronic stress in allergic disease and inflamma …